RNA
Part:BBa_K2923002
Designed by: claire husser Group: iGEM19_Strasbourg (2019-09-12)
Theophylline inactif aptazyme
an aptazyme is an aptamer-ribozyme combinations with intrinsic RNA cleavage activity. this aptazyme is specific for the theophylline (liguant). Theophylline (1,3-dimethylxanthine) is a drug used in therapy for respiratory diseases and is structurally similar to theobromine and caffeine He is composed in 3 differents part, a twister ribozyme module, a communication module and an aptamer module This aptazyme is an inactive aptazyme, this mean that the ribozyme part is mutated and the aptazyme lost his capacity to self-cleave. you can use it as a negative control fot the part: BBa_K2923001
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
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Categories
Parameters
//classic/rna/uncategorized
ligands | Theophylline |
switch_point | 2.5 mM of Theophylline |