Reporter
NG5
Part:BBa_K2623025
Designed by: Yunyun Hu Group: iGEM18_XMU-China (2018-10-02)
Archaeal ribosomal protein protein L7Ae fused with SpyCatcher and mRFP1.
Archaeal ribosomal protein protein L7Ae owns the ability to bind with RNA with C/Dbox RNA structure. Through the isopeptide bonds formed between SpyTag and SpyCatcher, L7Ae can be anchored with OmpA, and then secreted into OMVs. To transport our L7Ae into the periplasmic space, we inserted TorA leader sequence to the circuitry. mRFP1 is conjugated with L7Ae to validate the SpyTag/SpyCatcher bioconjugation.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 1168
Illegal NheI site found at 1191 - 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 2325
Illegal AgeI site found at 2437 - 1000COMPATIBLE WITH RFC[1000]
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Categories
Parameters
None |