Regulatory

Part:BBa_K2865000:Design

Designed by:   Group: iGEM18_SMMU-China   (2018-09-22)
Revision as of 12:02, 22 September 2018 by Registry (Talk | contribs)

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BNP promoter, heart failure inducible


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI site found at 242


Design Notes

We selected this range of sequence for it contains several regulatory elements and could be activated by a few factors, including endothelin (ET), angiotensin II (Ang II), and hypoxia.


Source

This promoter is synthesized from Homo sapiens natriuretic peptide precursor B (NPPB) gene.

References