Part:BBa_K2309025

Grammistin-Pp1 is an antimicrobial peptide secreted by soapfish with 13-residue long. This peptide is secreted to protect the fish themselves from pathogenic implantation and/or to kill pathogenic microbes. According to the research, this peptide can inhibit the growth of Gram-positive and Gram-negative bacteria at µM levels because of the interaction between membrane phospholipids and Grammistin-Pp1. The Grammistin-Pp1 has alpha helix structure, which contains positive charge. We pick it because this peptide shown to be lethal against S. aureus.