Coding

Part:BBa_K2271103:Design

Designed by: Jan Maika and Philipp Rink   Group: iGEM17_Cologne-Duesseldorf   (2017-10-27)
Revision as of 16:01, 31 October 2017 by Jan-maika (Talk | contribs) (→‎References)


pex15


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

The part was designed as a membrane anchor for the v-SNARE Snc1 to secrete peroxisomes.

Source

Synthesized by IDT.

References

[1] Targeting of the tail-anchored peroxisomal membrane proteins PEX26 and PEX15 occurs through C-terminal PEX19-binding sites.
André Halbach, Christiane Landgraf, Stephan Lorenzen, Katja Rosenkranz, Rudolf Volkmer-Engert, Ralf Erdmann, and Hanspeter Rottensteiner (2006)
Journal of Cell Science 119, 2508-2517 Published by The Company of Biologists 2006 doi:10.1242/jcs.02979

[2] Overexpression of Pex15p, a phosphorylated peroxisomal integral membrane protein required for peroxisome assembly in S.cerevisiae, causes proliferation of the endoplasmic reticulum membrane.
Ype Elgersma, Liane Kwast, Marlene van den Berg, William B. Snyder, Ben Distel, Suresh Subramani, Henk F. Tabak(1997)
EMBO J 16(24):7326-41 DOI 10.1093/emboj/16.24.7326