Composite
Part:BBa_K2323000:Design
Designed by: Jorge Andres Quintero Serna Group: iGEM17_Munich (2017-10-25)
Lwa Cas13a + Tphi terminator
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BglII site found at 1286
Illegal BglII site found at 2966 - 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI.rc site found at 2365
Design Notes
The protein is quite large, and therefore the sequence should be codon-optimized for the organism and strain it will be expressed in. We checked that there was no excessive use of rare codons for expression in E.coli, and used the strain Rosetta2 which contains an additional plasmid for rare codons.
Source
Leptotrichia wadei