Coding

Part:BBa_K2130000

Designed by: Ooi Kean Hean   Group: iGEM16_NTU-Singapore   (2016-10-19)
Revision as of 04:44, 22 October 2016 by OOIK0003 (Talk | contribs)


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dCas9 is a catalytically inactive Cas9, which still retains it's ability to bind to DNA. For epigenetic regulation, the dCas9 is highly dependent upon the function of it's fusion partner. For this part, we have deleted the HNH domain of the SP-dCas9 and tested it's binding capability by assessing the strength in transcriptional activation via a VP64-p65-Rta.



T--NTU-Singapore--ruvc3delresult.png


Sequence and Features No part name specified with partinfo tag.


[edit]
Categories
//awards/basic_part/nominee
Parameters
None