Coding
Part:BBa_K2165000:Design
Designed by: Roya Amini-Naieni Group: iGEM16_Washington (2016-10-14)
Violacein C gene codon-optimized for S. Cerevisiae
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI.rc site found at 101
Design Notes
The online codon-optimization tool offered by Integrated DNA Technologies (https://www.idtdna.com/CodonOpt) was used to codon-optimize this sequence for use in yeast. Combinations containing RFC 10 illegal restriction sites were actively avoided.
Source
VioC is originally from the violacein metabolic pathway in Chromobacterium Violaceum, a type of Proteobacteria. The original vioC sequence for the bacteria chassis was submitted by the Alberta team and has been codon-optimized for use in yeast in this part.