Device

Part:BBa_K1613006

Designed by: Ko-yu Chang   Group: iGEM15_HSNU-TAIPEI   (2015-09-05)
Revision as of 03:16, 6 September 2015 by Registry (Talk | contribs)

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A composite part that can detect some toxins.

cyp1a2 can oxidize the substances that it can metabolism. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP1A2 is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include aflatoxin B1, and acetaminophen.

Sequence and Features


Assembly Compatibility:
  • 10
    INCOMPATIBLE WITH RFC[10]
    Illegal prefix found in sequence at 65
    Illegal suffix found in sequence at 1654
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal EcoRI site found at 65
    Illegal NheI site found at 7
    Illegal NheI site found at 30
    Illegal SpeI site found at 1655
    Illegal PstI site found at 1669
    Illegal NotI site found at 71
    Illegal NotI site found at 1662
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal EcoRI site found at 65
    Illegal BglII site found at 1484
  • 23
    INCOMPATIBLE WITH RFC[23]
    Illegal prefix found in sequence at 65
    Illegal suffix found in sequence at 1655
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal prefix found in sequence at 65
    Illegal XbaI site found at 80
    Illegal SpeI site found at 1655
    Illegal PstI site found at 1669
    Illegal NgoMIV site found at 404
    Illegal NgoMIV site found at 491
    Illegal AgeI site found at 474
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal BsaI.rc site found at 1204


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Parameters
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