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Part:BBa_K1590001

Designed by: Manuel Blank   Group: iGEM15_Dundee   (2015-09-08)
Revision as of 20:51, 18 September 2015 by Franksargent (Talk | contribs)

Human Haemoglobin B

Human haemoglobin (hemoglobin) forms a tetramer consisting of two A-chains and two B-chains. This biobrick is a synthetic gene encoding the human haemoglobin B-chain that has been optimized for expression in E. coli.

Usage and Biology

Haemoglobin is the tetrameric protein molecule in red blood cells that carries oxygen. It is composed of four polypeptide chains, which in adults consist of two alpha (A) globin chains and two beta (B) globin chains. The protein also normally contains the iron-containing cofactor haem (or heme). Haemoglobin can still be found free in the blood plasma at a concentration of up to 0.1 g/l.


Results

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Parameters
None