Coding

Part:BBa_K1071002

Designed by: Team Marburg 2013   Group: iGEM13_Marburg   (2013-09-19)
Revision as of 10:56, 29 September 2013 by ChristianM (Talk | contribs)

cat resistance (procaryotic)

Chloramphenicol interacts with the 50s Subunit of bacterial ribosomes and blocks peptidyltransferase activity. The antibiotic is acting on gram negative as well as on gram positive bacteria. The enzyme Chloramphenicol acetyltransferase (CAT) transfers one or two Acetyl groups to the hydroxyl-Residues of Chloramphenicol. This inactivates the antibiotic.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None