Coding

Part:BBa_K1190000

Designed by: Nisarg Patel   Group: iGEM13_Arizona_State   (2013-08-30)
Revision as of 10:42, 5 October 2013 by Napatel (Talk | contribs)

Melan-A (MART-1)

Protein melan-A is a protein that in humans is encoded by the MLANA gene. A fragment of the protein, usually consisting of the nine amino acids 27 to 35, is bound by MHC class I complexes which present it to T cells of the immune system. These complexes can be found on the surface of melanoma cells. Decameric peptides (26-35) are being investigated as cancer vaccines.

This parts has been sequence confirmed, quantitatively deonstrating correct identification of biobrick.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None