Coding

Part:BBa_K1162001

Designed by: Charles Barentine   Group: iGEM13_Utah_State   (2013-09-15)
Revision as of 00:38, 28 September 2013 by Ryanputman (Talk | contribs)

EcAMP-1 antimicrobial peptide from barnyard grass (Echinochloa crus-galli)

EcAMP-1 is derived from the grass species Echinochloa crus-galli. It consists of 37 amino acids and is helical in structure, held together by two disulfide bonds. This feature enables a unique hairpin structure which is not found in most other AMPs. EcAMP-1 has shown to have a toxic affect against a variety of fungi and protists. The mode of action for EcAMP-1 against fungi appears to be the prevention of hyphae elongation.


RFC 23 compatible. Contains ATG (methionine).

Usage and Biology

References

Nolde, S., Vassilevski, A., Rogozhin, E., Barinov, N., Balashova, T., Samsonova, O., Baranov, Y., Feofanov, A., Egorov, A., Arseniev, A., Grishin, E., Disulfide-stabilized Helical Hairpin Structure and Activity of a Novel Antifungal Peptide EcAMP1 from Seeds of Barnyard Grass (Echinochloa crus-galli). The Journal of Biological Chemistry. 2011. 286: 25145-25153.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
//collections/antimicrobial
Parameters
None