Help:Regulatory

Revision as of 16:49, 7 July 2006 by Smelissali (Talk | contribs) (→‎Inducible parts)

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Regulatory parts are those which provide binding regions for RNA polymerase, the enzyme which performs the act of transcription (the conversion of DNA to RNA).
Some sub-categories of Regulatory parts are:


Constitutive parts

  • constituitive: parts which allow for continual transcription of parts. Often these parts can be de-activated by the addition of ligand. The use of constituitive promoters can be desirable since they are less susceptible to cross-talk and can hypothetically take in PoPS input.

Examples of constitutive parts include

  • Part:BBa_R0040 - the pTet promoter region, controlled by tetracycline or its chemical analog [http://openwetware.org/wiki/ATc ATC]
  • Part:BBa_R0010 - the pLac promoter region, controlled by the lactose protein or by its chemical analog [http://openwetware.org/wiki/IPTG IPTG]



Inducible parts

Parts which are continually "off" (transcription is not induced), but allow for activation (increase transcription) through the addition of particular chemicals
Examples include:

  • Part:BBa_R0080 - The araC promoter region, which can be activated by the addition of the sugar [http://openwetware.org/wiki/Arabinose arabinose]
  • Part:BBa_I0500 - Another [http://openwetware.org/wiki/Arabinose arabinose] inducible promoter region