Coding
dszB
Part:BBa_K902052:Design
Designed by: Lisa Oberding, Ali Honarmand Group: iGEM12_Calgary (2012-10-01)
HBPS desulfinase (DszB) from R. erythropolis (mutated for improved activity)
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BamHI site found at 426
Illegal XhoI site found at 418 - 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 133
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
Mutations of internal PstI and NotI cut sites in order to make biobrick compatible, as well as an added mutation of Y63F in the protein to increase its activity.
Source
Amplified from a plasmid in an environmental isolate of Rhodococcus shown to be an active desulfurizer.