Coding

Part:BBa_K902030

Designed by: Emily Hicks   Group: iGEM12_Calgary   (2012-10-02)
Revision as of 00:58, 4 October 2012 by Kevinm.huie (Talk | contribs)

Manganese homeostatic regulation (mntR)

The mntR metalloregulatory protein is native to the Escherichia coli K-12 strain. This transcriptional regulator is found to observe the level of manganese and responds accordingly. The structure of this protein consists of a metal-binding domain that will respond in the presence of manganese and repress the small RNA gene mntS. Lack of mntS will then repress the manganese ion transporter (mntH) as 42-amino-acid protein forms. When this protein membrane is repress the bacteria cannot gained the needed manganese. It is also found that the mntR positively regulates the mntP a putative efflux pump that regulates the intracellular level of manganese.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    INCOMPATIBLE WITH RFC[1000]
    Illegal SapI.rc site found at 58


[edit]
Categories
Parameters
None