Coding

Part:BBa_K875009

Designed by: Giulia Corso, Sara Samari   Group: iGEM12_Trieste   (2012-09-23)
Revision as of 14:56, 24 September 2012 by Corsogiulia (Talk | contribs)

LL 37 - Cathelicidin

The LL 37 cathelicidin is a human antimicrobial peptide. The antimicrobial peptides (AMPs) are present in all species investigated. They form an important part of innate immunity, protecting the organism from infection by directly killing invading bacteria. It disrupts the bacteria membrane from outside and it is armless from inside. (Ulrich et al., 2006)

The eukaryotic toxin LL 37 was obtained by synthesis with the canonical prefix and suffix RFC10 compatible and it was optimized for E. coli expression.




Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
//chassis/prokaryote/ecoli/nissle
//collections/antimicrobial
//collections/probiotics
//collections/probiotics/biocontainment
Parameters
None