Coding
Part:BBa_K533006:Design
Designed by: ZHANG Yunxiao Group: iGEM11_Tsinghua (2011-09-29)
Multi-Proline-mCherry
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BglII site found at 109
Illegal BamHI site found at 908
Illegal XhoI site found at 113 - 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
proline rich sequence is much longer than the length required for SH3 binding, for easier binding to SH3 domain.
Source
mCherry sequence is from Clontech plasmid pmCherry-N1 and multi-proline sequence is synthesized from a consensus sequence of SH3 binding sequence.