Coding
T7Amb
Part:BBa_K606032
Designed by: Axel Séguret Group: iGEM11_Paris_Bettencourt (2011-09-18)
T7 RNA polymerase with tyrosine amber codons
T7 RNA polymerases where two tyrosines were mutated to an amber (stop) codons.
Usage and Biology
The T7 RNA polymerases have two stops codons at the begening of its sequence. The protein cannot be expressed unless a tRNA amber supressor is expressed in the cell. (for instance K606034 for B. subtilis). This strategy can be use to create an and gate. If you want then the signal to be amplify, you can unse both K606018 or K606035 for reporting.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
[edit]
Categories
Parameters
//cds/enzyme
None |