Coding
Part:BBa_K364201:Design
Designed by: Lior Malka Group: iGEM10_Debrecen-Hungary (2010-08-05)
Human RXR DBD
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
The construction of the DBD and Backbone have been done with RFC 25.
Source
Human RXRalpha (of nuclear receptor superfamily). Artifically synthetized DNA Binding Domain of Human RXRalpha, placed into pSB1C3 carrier vector.
References
Kliewer S, Goodwin B, Willson T (2002). "The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism". Endocr. Rev. 23 (5): 687–702. doi:10.1210/er.2001-0038. PMID 12372848.