Composite
Part:BBa_K5520011:Design
Designed by: Ruyi Shi Group: iGEM24_Ulink-SZ (2024-09-29)
pT7-LacO-His- CsnBP115A
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 844
Illegal NotI site found at 804 - 21INCOMPATIBLE WITH RFC[21]Illegal XhoI site found at 813
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 153
Illegal AgeI site found at 636 - 1000COMPATIBLE WITH RFC[1000]
Design Notes
We aimed to investigate the relationship between the structure and function of chitosanase and to produce chitooligosaccharides with a defined degree of polymerization. To achieve this, amino acid mutation at site 115 was engineered to enhance enzymatic activity and to generate more uniform products.
Source
Escherichia coli and Bacillus pumilus