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Part:BBa_K5507008:Experience

Designed by: josiazhang josiazhang   Group: iGEM24_HW-ShanghaiUnited   (2024-09-29)
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Applications of BBa_K5507008

User Reviews

UNIQaacfb01c36e5f195-partinfo-00000000-QINU UNIQaacfb01c36e5f195-partinfo-00000001-QINU

a. Construction of BBa_K5507008 For the overexpression of the pgi gene from E. coli, the sacB locus, which encodes levansucrase, was selected as a homologous recombination site because knocking out this gene has no metabolic effects under glucose conditions. First, the kana expression cassette will replace the sacB gene locus as a selectable marker. Then, pgi will replace the kana gene, resulting in the loss of kana resistance, confirming successful gene insertion.

< img src = "https://static.igem.wiki/teams/5507/parts-figures/hw-figure-1.png" style = "width:500px">
Figure 1. Gene map of BBa_K5507008