Coding

Part:BBa_K4585000

Designed by: Siyao Ma   Group: iGEM23_CSU-CHINA   (2023-09-22)
Revision as of 01:37, 9 October 2023 by Kaye (Talk | contribs)


GnRH-C

A protein of truncated gonadotropin-releasing hormone.GnRH secreted by the hypothalamus plays an important role in the regulation of vertebrate reproduction. It is a peptide of 10 amino acids, which can be synthesized artificially. It can release luteinizing hormone and follicle stimulating hormone. It is mainly distributed in the lateral area of median eminence, as well as in arcuate nucleus, preoptic area of hypothalamus, ependymal cells and pineal gland.

Insulin

We have proved that Insulin can be processed and secreted outside the cell in 293T cells.

1.diagram

Fig.1 The model diagram of GnRH-C

2.Agarose gel electrophoresis map

Fig.2 The agarose gel electrophoresis map of GnRH-C fragment PCR product

3.Caution

GnRH-C is the result of truncation of full-length GnRH.

4.Reference:

[1]Mingqi Xie, Haifeng Ye, Hui Wang.β-cell-mimetic designer cells provide closed-loop glycemic control[J].Science.2016 Dec 9;354(6317):1296-1301.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


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Categories
Parameters
None