Part:BBa_K4601005
NpSRII
This part is the NpSRII sensory rhodopsin.
Usage and Biology
NpSRII is a sensory rhodopsin identified in the archaea Natronomonas pharaonis.
Sensory rhodopsins are not pumps, but photoreceptors that respond to light and transmit the signal into the cell via a signaling cascade. For this, in N. pharaonis, NpSRI and NpSRII interact with the transducer proteins NpHtrI and NpHtrII, respectively [1]. NpHtrI and NpHtrII are homodimeric membrane proteins that have also a cytoplasmic histidine kinase domain responsible for initiating the signaling cascade that mediates chemotaxis. The interaction between the SR and their cognate Htr transducers are highly specific.
References
[1] Jung KH, Spudich EN, Trivedi VD, Spudich JL. An archaeal photosignal-transducing module mediates phototaxis in Escherichia coli. Journal of Bacteriology (2001) 183: 6365–6371.
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 73
Illegal NgoMIV site found at 331 - 1000COMPATIBLE WITH RFC[1000]
None |