Signalling

Part:BBa_K4586020

Designed by: Mohamed Mohamed Saad Aboelghare   Group: iGEM23_AFCM-Egypt   (2023-09-15)
Revision as of 10:13, 21 September 2023 by Mohamed-Ab0elghare (Talk | contribs)


SV40 NLS

Part Description

Nuclear localization signals are short peptides that are responsible for the transport of nuclear protein from the cytoplasm to the nucleus to perform its function.

Usage

We used this basic part in our design to mediate the transfer of our transcription module VP64 into the nucleus to carry out its action on the target promoter that regulates the expression of our therapeutic agent (Cass12k).





Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None