Coding
Part:BBa_K4882001
Designed by: Yuqi Fu Group: iGEM23_Hangzhou-SDG (2023-06-28)
LqhIT2, an insect-specific toxin from Leiurus quinquestriatus hebraeus
LqhIT2 is a 61 amino acid-long scorpion depressant toxin from L. quinquestriatus hebraeus. Although the scorpion is dangerous to humans, LqhIT2 is not. LqhIT2 shows a high preference for insect voltage-gated sodium channels and is totally harmless to mammals (Karbat et al., 2007; Zlotkin et al., 1991).
Usage and Biology
Since LqhIT2 is only toxic to insects, it is a good choice for pesticides. To improve the efficiency and effectiveness of Metarhizium anisopliae as a fungal biopesticide, we chose to introduce LqhIT2 into the fungus. LqhIT2 significantly improved the virulence of M. anisopliae against pests.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BamHI site found at 88
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
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Categories
Parameters
None |