Protein_Domain

Part:BBa_K4165066

Designed by: Ahmed Sameh   Group: iGEM22_CU_Egypt   (2022-09-30)
Revision as of 08:22, 11 October 2022 by Esraa Elmligy (Talk | contribs)


GSGSG Linker

A flexible 5 aa Glycine-Serine Linker.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]

Dry Lab Characterization

In our project, we generated a library for GS flexible linkers to be tested on different parts of our system; each linker was modeled in the fusion protein, and we filtered through them until we found the suitable length to use in linking our PROTAC, clamps, and switches together.

References

1- Yuan, S., Chan, H. S., & Hu, Z. (2017). Using pymol as a platform for computational drug design. WIREs Computational Molecular Science, 7(2). doi:10.1002/wcms.1298


[edit]
Categories
Parameters
None