Regulatory
Part:BBa_K4129002
Designed by: Giovanni Carlo Gendarini Group: iGEM22_DTU-Denmark (2022-10-02)
Promoter of the Aspergillus niger FDH gene
The part consists of the 1000 bp upstream of Formate Dehydrogenase (FDH) CDS from Aspergillus niger. Since FDH genes have been shown to be upregulated in response to furfural in Saccharomyces cerevisiae, the part was utilised to test if anFDH promoter is also responsive to furfural. When used to drive expression of mCherry in A. niger through transient expression, the promoter does not appear to be induced by furfural or does not promote expression at levels high enough to be detected during transient expression.
Sequence and Features
Assembly Compatibility:
- 10INCOMPATIBLE WITH RFC[10]Illegal SpeI site found at 34
Illegal SpeI site found at 160 - 12INCOMPATIBLE WITH RFC[12]Illegal SpeI site found at 34
Illegal SpeI site found at 160 - 21COMPATIBLE WITH RFC[21]
- 23INCOMPATIBLE WITH RFC[23]Illegal SpeI site found at 34
Illegal SpeI site found at 160 - 25INCOMPATIBLE WITH RFC[25]Illegal SpeI site found at 34
Illegal SpeI site found at 160 - 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI site found at 564
Illegal BsaI site found at 929
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Categories
Parameters
None |