DNA
UreR
Part:BBa_K3710002
Designed by: Luke Roche, Sandra Martinez Diaz, Erik Hanko and Katherine Baker Group: iGEM21_Manchester (2021-09-29)
UreR: urea-responsive transcriptional regulator
This part encodes the urea-responsive transcriptional regulator UreR, optimised for E. coli codon usage. Proteus mirabilis encodes the transcriptional regulator UreR of the urease gene cluster. It belongs to the AraC/XylS family of transcriptional regulators. UreR upregulates the gene clusters’ subunit transcription in the presence of urea and recruits the accessory proteins (UreDABCEFG),forming an active urease [1].
References:
[1] Poore, C. and Mobley, H. (2003) "Differential regulation of the Proteus mirabilis urease gene cluster by UreR and H-NS", Microbiology, 149(12), pp. 3383-3394.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
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Categories
Parameters
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