Protein_Domain
Part:BBa_K3740006
Designed by: Guiyi Huang Group: iGEM21_SZPT-CHINA (2021-08-26)
Receptor binding domain of Pyocin S2
Description
We used it to construct chimeric bacteriocin SE
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
2021 SZPT-China
Biology
Bacteriocin activity proteins have three distinct domains arranged from N to C terminus that include receptor,translocase,and nuclease (with immunity protein-binding) domains. The receptor binding domain are species specifific,and it can bind the corresponding receptor FpyA on the surface of P.aeruginosa.
References
[1] Gupta S, Bram E E, Weiss R. Genetically programmable pathogen sense and destroy. [J]. Acs Synthetic Biology, 2013, 2(12):715-723.
<p>[2] Michel-Briand Y, Baysse C. The pyocins of Pseudomonas aeruginosa. [J]. Biochimie, 2002, 84(5-6):499-510
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Categories
Parameters
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