Coding

Part:BBa_K3989023

Designed by: Song-Yuan Zhang   Group: iGEM21_UZurich   (2021-10-01)
Revision as of 00:13, 20 October 2021 by ZhangSongyuan (Talk | contribs)


elf18

Elf18 is a peptide consisting of 18 conserved amino acids at the N-terminus of bacterial elongation factor Tu (EF-Tu), the most abundant bacterial protein.

As a microbe- or pathogen-associated molecular pattern (MAMP or PAMP), elf18 can trigger strong plant immune responses, such as cell-wall reinforcement by callose deposition, production of reactive oxygen species (ROS), and induction of numerous defense-related genes. However, unlike another PAMP flg22, which is perceived by most plants through FLS2 receptor, elf18 can be only perceived by Brassicaceae through EFR receptor.

At least in A. thaliana, elf18 can trigger stronger immune responses than flg22.

Flg22vself18.png

Reference:

[1] Kunze, G., Zipfel, C., Robatzek, S., Niehaus, K., Boller, T., & Felix, G. (2004). The N terminus of bacterial elongation factor Tu elicits innate immunity in Arabidopsis plants. The Plant Cell, 16(12), 3496-3507.

[2] Zipfel, C., Kunze, G., Chinchilla, D., Caniard, A., Jones, J. D., Boller, T., & Felix, G. (2006). Perception of the bacterial PAMP EF-Tu by the receptor EFR restricts Agrobacterium-mediated transformation. Cell, 125(4), 749-760.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
//awards/basic_part/nominee
Parameters
None