Composite
CEAker
Part:BBa_K3284001
Designed by: Bella Stevanny, Mutiara Tri Florettira, Ragil Cahyati Group: iGEM19_Sriwijaya (2019-10-20)
Revision as of 21:03, 21 October 2019 by Bellastevanny (Talk | contribs)
TGFbRI/Taz Chimeric Receptor Device
This part is a chimeric between extracellular (CEA-sensing) domain of Homo sapiens transforming growth factor beta receptor I (TGFbRI) receptor and transmembrane+intracellular domain of Escherichia coli Tar/EnvZ receptor.
Usage and Biology
This part can be used to detect B3 domain of CEA (carcinoembryonic antigen) as it has CEA binding domain of type II TGF-β receptor (TβRII). The binding results in the activation of signalling pathway in E. coli as it has Tae/EnvZ transmembrane+intracellular domain.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
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Categories
Parameters
//awards/basic_part
None |