Part:BBa_K3241029:Experience

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    In R. eutropha cells, PHB is made through 3 steps.Two acetyl-CoA molecules made from carbohydrate converted to acetoacetyl-CoA by β-ketothiolase by PhbA gene. Then acetoacetyl-CoA reductase encoded by PhbB gene catalyzes the reduction of acetoacetyl-CoA to (R)-3-hydroxybutyryl-CoA (3HB-CoA). Finally, PHB synthase encoded by PhbC gene catalyzes polymerization reaction of monomer molecules to PHB.

left Fig.1 PHB panthway genes.