Coding

Part:BBa_K3096030:Design

Designed by: Lina Widerspick, Famke Baeuerle, Patrick Mueller, Jakob Keck   Group: iGEM19_Tuebingen   (2019-10-14)
Revision as of 12:42, 15 October 2019 by Lina widerspick (Talk | contribs) (→‎References)

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Exendin-4 (GLP-1 analogue) with secretion signal


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

no changes were made to the sequence


Source

KR 1020120130606-A/1: Secretion signal peptide linked Exendin-4 gene transduced pancreatic islet cluster for treatment of type I diabetes

References

Jens Juul Holst. The Physiology of Glucagon-like Peptide 1. (2007). Physiological Reviews. p.1409-1439. https://www.physiology.org/doi/abs/10.1152/physrev.00034.2006

KR 1020120130606-A/1: Secretion signal peptide linked Exendin-4 gene transduced pancreatic islet cluster for treatment of type I diabetes

Lim, Gareth E., Brubaker, Patricia L. Glucagon-Like Peptide 1 Secretion by the L-Cell. (2006). 10.2337/db06-S020. Diabetes. p. S70-S77

Copley, Kathrin & McCowen, Kevin & Hiles, Richard & L Nielsen, Loretta & Young, Andrew & Parkes, David. (2006). Investigation of Exenatide Elimination and Its In Vivo and In Vitro Degradation. Current drug metabolism. 7. 367-74. 10.2174/138920006776873490.