Regulatory

Part:BBa_K2610000

Designed by: Marjolein Crooijmans   Group: iGEM18_Leiden   (2018-10-09)
Revision as of 20:12, 15 October 2018 by Chardeceuninck (Talk | contribs)


pAlkA

AlkA, a gene under regulation of the adaptive response, is involved in the DNA damage response of Escherichia coli and can be upregulated upon exposure to DNA alkylating agents. AlkA encodes 3-methyladenine glycosylase II, a repair glycosylase. Previous research has shown a specific response of this gene to alkylating agents when coupled to luxCDABE. <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975202/">(Bowmanet al. 2010).</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815808/">(Biran al. 2010).</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmed/9212407">(Vollmer al. 1997).</a>

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None