Coding
accB

Part:BBa_K2588011

Designed by: Bjarne Klopprogge   Group: iGEM18_Hamburg   (2018-10-05)
Revision as of 10:46, 17 October 2018 by BKlopprogge (Talk | contribs)


Acetyl-CoA biotin carboxyl carrier protein

Usage and Biology

The Acetyl-CoA carboxyl carrier protein is part of the acetyl-CoA carboxylase ACC, which is the major regulator for fatty acid biosynthesis in e. coli. It is encoded as a single mRNA with the downstream accC, which is encoding for the biotin carboxylase of the complex.1 The acetyl-CoA biotin carboxyl carrier protein binds with biotin and transfers carboxylated biotin to the acetyl-CoA carboxyltransferase.2

References

  1. Li, S. J. & Cronan, J. E. The gene encoding the biotin carboxylase subunit of Escherichia coli acetyl-CoA carboxylase. J. Biol. Chem. 267, 855–63 (1992).
  2. Broussard, T. C., Price, A. E., Laborde, S. M. & Waldrop, G. L. Complex formation and regulation of escherichia coli acetyl-CoA carboxylase. Biochemistry (2013). doi:10.1021/bi4000707


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal AgeI site found at 432
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None