Coding

Part:BBa_K2486112

Designed by: Tiago Lubiana Alves   Group: iGEM17_USP-Brazil   (2017-10-27)
Revision as of 04:17, 28 October 2017 by Lubdub (Talk | contribs)

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Anti-malarial peptide (SM1)2

[theoretical part] [not assembled, not synthesized, not sent, not characterized]

Anti malarial peptide that binds to the luminal side of the midgut epithelium of Anopheles mosquitos. (1) Used in paratransgenic approaches to block Plasmoidum transmission. (2)

1- Ghosh, Anil K., Paulo EM Ribolla, and Marcelo Jacobs-Lorena. "Targeting Plasmodium ligands on mosquito salivary glands and midgut with a phage display peptide library." Proceedings of the National Academy of Sciences 98.23 (2001): 13278-13281. APA

2 - Wang, Sibao, et al. "Driving mosquito refractoriness to Plasmodium falciparum with engineered symbiotic bacteria." Science 357.6358 (2017): 1399-1402.

Sequence codon optized to E. coli with https://www.idtdna.com/CodonOpt

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None