Coding

Part:BBa_K1611004

Designed by: Frederic Ros   Group: iGEM15_Evry   (2015-09-15)
Revision as of 22:45, 18 September 2015 by Evry Entrepreneur (Talk | contribs)

DEC-205

This is a scFv antibody against DEC205. DEC205 is an endocytic receptor that is expressed by dendritic cells. Antigen endocytosed via DEC205 enters the MHC class I and MHC class II antigen presentation pathways and is subsequently presented to both CD4+ and CD8+ T cells. We used it to activate T-CD8 cells, with tumorous antigen that we binded to DEC205 scFv.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BamHI site found at 533
    Illegal XhoI site found at 414
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
//chassis/eukaryote/yeast
Parameters
None