Coding
Part:BBa_K1720000:Design
Designed by: YuanbinCui Group: iGEM15_SCUT-China (2015-08-09)
Human guanylate cyclase1,soluble, alpha 3 unit
Assembly Compatibility:
- 10INCOMPATIBLE WITH RFC[10]Illegal PstI site found at 1498
Illegal PstI site found at 1827 - 12INCOMPATIBLE WITH RFC[12]Illegal PstI site found at 1498
Illegal PstI site found at 1827 - 21COMPATIBLE WITH RFC[21]
- 23INCOMPATIBLE WITH RFC[23]Illegal PstI site found at 1498
Illegal PstI site found at 1827 - 25INCOMPATIBLE WITH RFC[25]Illegal PstI site found at 1498
Illegal PstI site found at 1827 - 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI.rc site found at 1576
Illegal SapI site found at 1446
Design Notes
This part do not contains promoter so that users can add their own promoter vary from different purpose.
Source
http://www.ncbi.nlm.nih.gov/gene/2982
References
1. Gheorghiade M, Marti CN, Sabbah HN, Roessig L, Greene SJ, Bohm M, Burnett JC, Campia U, Cleland JG, Collins SP et al:
Soluble guanylate cyclase: a potential therapeutic target for heart failure. Heart failure reviews 2013, 18(2):123-134.
2. Sharina IG, Cote GJ, Martin E, Doursout MF, Murad F: RNA splicing in regulation of nitric oxide receptor soluble guanylyl
cyclase. Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2011, 25(3):265-274.
3. Marinko M, Novakovic A, Nenezic D, Stojanovic I, Milojevic P, Jovic M, Ugresic N, Kanjuh V, Yang Q, He GW: Nicorandil directly
and cyclic GMP-dependently opens K channels in human bypass grafts. Journal of pharmacological sciences 2015.