Regulatory

Part:BBa_K1328000

Designed by: Tianyi Li   Group: iGEM14_Tsinghua   (2014-10-09)
Revision as of 15:50, 17 October 2014 by Lester (Talk | contribs)

HXT1-CMVmini 2014-HXT1%2BCMV-forget.png

Part HXT1+CMV is used as promoter for target gene under the regulation of glucose, consisting of HXT-1 promoter and CMV promoter.

HXT-1 is a low-affinity glucose transporter from Saccharomyces cerevisiae. There is a glucose response element in HXT-1 gene sensitive to glucose in human fibroblasts, which is used here as a glucose-dependent regulator.

Expression of target gene under the control of HXT1-CMV promoter is induced by high concentration of glucose.

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