Part:BBa_K1162001

EcAMP-1 antimicrobial peptide from barnyard grass (Echinochloa crus-galli)

EcAMP-1 is derived from the grass species Echinochloa crus-galli. It consists of 37 amino acids and is helical in structure, held together by two disulfide bonds. This feature enables a unique hairpin structure which is not found in most other AMPs. EcAMP-1 has shown to have a toxic affect against a variety of fungi and protists. The mode of action for EcAMP-1 against fungi appears to be the prevention of hyphae elongation.

RFC 23 compatible. Contains ATG (methionine).

References

Nolde, S., Vassilevski, A., Rogozhin, E., Barinov, N., Balashova, T., Samsonova, O., Baranov, Y., Feofanov, A., Egorov, A., Arseniev, A., Grishin, E., Disulfide-stabilized Helical Hairpin Structure and Activity of a Novel Antifungal Peptide EcAMP1 from Seeds of Barnyard Grass (Echinochloa crus-galli). The Journal of Biological Chemistry. 2011. 286: 25145-25153.

Sequence and Features

Assembly Compatibility:

• 10
  COMPATIBLE WITH RFC[10]
• 12
  COMPATIBLE WITH RFC[12]
• 21
  COMPATIBLE WITH RFC[21]
• 23
  COMPATIBLE WITH RFC[23]
• 25
  COMPATIBLE WITH RFC[25]
• 1000
  COMPATIBLE WITH RFC[1000]