Part:BBa_K727007:Design

Rose Odor Generator Device (Geraniol)

Assembly Compatibility:

• 10
  INCOMPATIBLE WITH RFC[10]

  Illegal prefix found in sequence at 1053
  Illegal suffix found in sequence at 1973
  Illegal EcoRI site found at 2002
  Illegal XbaI site found at 2017
  Illegal SpeI site found at 3832
  Illegal PstI site found at 3846
  
• 12
  INCOMPATIBLE WITH RFC[12]

  Illegal EcoRI site found at 1053
  Illegal EcoRI site found at 2002
  Illegal SpeI site found at 1974
  Illegal SpeI site found at 3832
  Illegal PstI site found at 1988
  Illegal PstI site found at 3846
  Illegal NotI site found at 1059
  Illegal NotI site found at 1981
  Illegal NotI site found at 2008
  Illegal NotI site found at 3839
  
• 21
  INCOMPATIBLE WITH RFC[21]

  Illegal EcoRI site found at 1053
  Illegal EcoRI site found at 2002
  
• 23
  INCOMPATIBLE WITH RFC[23]

  Illegal prefix found in sequence at 1053
  Illegal suffix found in sequence at 1974
  Illegal EcoRI site found at 2002
  Illegal XbaI site found at 2017
  Illegal SpeI site found at 3832
  Illegal PstI site found at 3846
  
• 25
  INCOMPATIBLE WITH RFC[25]

  Illegal prefix found in sequence at 1053
  Illegal EcoRI site found at 2002
  Illegal XbaI site found at 1068
  Illegal XbaI site found at 2017
  Illegal SpeI site found at 1974
  Illegal SpeI site found at 3832
  Illegal PstI site found at 1988
  Illegal PstI site found at 3846
  Illegal NgoMIV site found at 1330
  Illegal AgeI site found at 1235
  Illegal AgeI site found at 1616
  Illegal AgeI site found at 2183
  
• 1000
  INCOMPATIBLE WITH RFC[1000]

  Illegal BsaI.rc site found at 987
  

Design Notes

Optimized for E.coli

Source

Geraniol Producing Plants(Geranium, pelargonium etc.)

References

1. Babukumar, S., Vinothkumar, V., Sankaranarayanan, C., & Srinivasan, S. (2017). Geraniol, a natural monoterpene, ameliorates hyperglycemia by attenuating the key enzymes of carbohydrate metabolism in streptozotocin-induced diabetic rats. Pharmaceutical Biology, 55(1), 1442-1449. doi:10.1080/13880209.2017.1301494

2. Prasad, S. N., & Muralidhara. (2014). Protective effects of geraniol (a monoterpene) in a diabetic neuropathy rat model: Attenuation of behavioral impairments and biochemical perturbations. Journal of Neuroscience Research, 92(9), 1205-1216. doi:10.1002/jnr.23393

3. El-Bassossy, H. M., Ghaleb, H., Elberry, A. A., Balamash, K. S., Ghareib, S. A., Azhar, A., & Banjar, Z. (2017). Geraniol alleviates diabetic cardiac complications: Effect on cardiac ischemia and oxidative stress. Biomedicine & Pharmacotherapy, 88, 1025-1030. doi:10.1016/j.biopha.2017.01.131

4. El-Bassossy, H. M., Elberry, A. A., & Ghareib, S. A. (2016). Geraniol improves the impaired vascular reactivity in diabetes and metabolic syndrome through calcium channel blocking effect. Journal of Diabetes and Its Complications, 30(6), 1008-1016. doi:10.1016/j.jdiacomp.2016.04.006

5. Lei, Y., Fu, P., Jun, X., & Cheng, P. (2018). Pharmacological Properties of Geraniol – A Review. Planta Medica, 85(01), 48-55. doi:10.1055/a-0750-6907

6. Kaur, G., Ganjewala, D., Bist, V., & Verma, P. C. (2019). Antifungal and larvicidal activities of two acyclic monoterpenes; citral and geraniol against phytopathogenic fungi and insects. Archives of Phytopathology and Plant Protection, 52(5-6), 458-469. doi:10.1080/03235408.2019.1651579

7. Hyphae - Production, Structure, Morphology, Types. (n.d.). Retrieved October 26, 2020, from https://www.microscopemaster.com/hyphae.html

8. Liu, W., Xu, X., Zhang, R., Cheng, T., Cao, Y., Li, X., Guo, J., Liu, H., & Xian, M. (2016). Engineering Escherichia coli for high-yield geraniol production with biotransformation of geranyl acetate to geraniol under fed-batch culture. Biotechnology for biofuels, 9, 58. https://doi.org/10.1186/s13068-016-0466-5

9. Carrau, F. M., Medina, K., Boido, E., Farina, L., Gaggero, C., Dellacassa, E., Versini, G., & Henschke, P. A. (2005). De novo synthesis of monoterpenes by Saccharomyces cerevisiae wine yeasts. FEMS microbiology letters, 243(1), 107–115. https://doi.org/10.1016/j.femsle.2004.11.050