Difference between revisions of "Part:BBa K3183004"
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<partinfo>BBa_K3183004 short</partinfo> | <partinfo>BBa_K3183004 short</partinfo> | ||
| − | Quorum sensing transcription factor from <i>C. difficile</i>. It is one of the members of the two-component detection system, adapted from <i>C. difficile</i>, that is bound by AgrC2 in response to Autoinducing peptide (AIP), which phosphorylates it. The released phosphorylated AgrA2 dimerizes with itself and becomes active. Upon activation, it binds to AgrPromoter (<partinfo>BBa_K3183003</partinfo>) which results in upregulation of transcription. | + | Quorum sensing transcription factor from <i>C. difficile</i>. It is one of the members of the two-component detection system, adapted from <i>C. difficile</i>, that is bound by AgrC2 in response to Autoinducing peptide (AIP), which phosphorylates it. The released phosphorylated AgrA2 dimerizes with itself and becomes active. Upon activation, it binds to AgrPromoter (<partinfo>BBa_K3183003</partinfo>) which results in upregulation of transcription. This gene is located in C. difficile CD196 genome. |
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Revision as of 01:02, 21 October 2019
AgrA2 Quorum Sensing Transcription Factor; C. difficile
Quorum sensing transcription factor from C. difficile. It is one of the members of the two-component detection system, adapted from C. difficile, that is bound by AgrC2 in response to Autoinducing peptide (AIP), which phosphorylates it. The released phosphorylated AgrA2 dimerizes with itself and becomes active. Upon activation, it binds to AgrPromoter (BBa_K3183003) which results in upregulation of transcription. This gene is located in C. difficile CD196 genome.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Use by Team Oxford 2019
This transcription factor is part of our detection system in L. reuteri. The composite parts containing this AgrA2 protein are BBa_K3183102, and BBa_K3183300.