Difference between revisions of "Part:BBa K2961001"
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This part encodes for a segment of the genome corresponding to the wildtype CFTR gene. | This part encodes for a segment of the genome corresponding to the wildtype CFTR gene. | ||
This part is contrasted by BBa_K2961000, which encodes for the same segment but with a single nucleotide mutation that results in a variant of cystic fibrosis. | This part is contrasted by BBa_K2961000, which encodes for the same segment but with a single nucleotide mutation that results in a variant of cystic fibrosis. | ||
+ | |||
+ | Note that this part of the CFTR gene is conveniently located near a PAM site for Cpf1, so can be used in gRNA design. | ||
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Latest revision as of 01:37, 17 October 2019
CFTR Wildtype gene segment
This part encodes for a segment of the genome corresponding to the wildtype CFTR gene. This part is contrasted by BBa_K2961000, which encodes for the same segment but with a single nucleotide mutation that results in a variant of cystic fibrosis.
Note that this part of the CFTR gene is conveniently located near a PAM site for Cpf1, so can be used in gRNA design.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]