Difference between revisions of "Help:Regulatory"

Revision as of 16:48, 7 July 2006

Browse Regulatory parts!

Regulatory parts are those which provide binding regions for RNA polymerase, the enzyme which performs the act of transcription (the conversion of DNA to RNA).
Some sub-categories of Regulatory parts are:

Constitutive parts

• constituitive: parts which allow for continual transcription of parts. Often these parts can be de-activated by the addition of ligand. The use of constituitive promoters can be desirable since they are less susceptible to cross-talk and can hypothetically take in PoPS input.

Examples of constitutive parts include

• Part:BBa_R0040 - the pTet promoter region, controlled by tetracycline or its chemical analog [http://openwetware.org/wiki/ATc ATC]
• Part:BBa_R0010 - the pLac promoter region, controlled by the lactose protein or by its chemical analog [http://openwetware.org/wiki/IPTG IPTG]

Inducible parts

• ligand-activated: parts which are continually "off", but allow for activation through the addition of particular chemicals
  

Examples include:

• Part:BBa_R0080 - The araC promoter region, which can be activated by the addition of the sugar [http://openwetware.org/wiki/Arabinose arabinose]
• Part:BBa_I0500 - Another [http://openwetware.org/wiki/Arabinose arabinose] inducible promoter region