Coding
cheZ

Part:BBa_K629003

Designed by: Zilong WANG, Yi ZHENG   Group: iGEM11_SYSU-China   (2011-10-03)

cheZ, chemotaxis regulator, protein phosphatase for CheY

Usage and Biology
Chemotaxis is the cell’s system for directed movement which allows the cell to move towards nutrition sources as well as away from toxic substances. The chemotactic system is a complex chain of phosphorylation reactions. At the end of the chain is the flagellum-binding protein CheY. The phosphorylated CheY (CheY-p) binds the flagella and causes the cell to tumble in place, essentially remaining immotile. The phosphatase CheZ dephosphorylates CheY, causing CheY to unbind to the flagella, resulting in directed movement of the cell [1].

References
[1] Madigan MT, Martinko JM, Stahl DA, Clark DP. 2010. Brock biology of microorganisms. 13th ed. Benjamin Cummings, San Francisco.
Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
//cds/enzyme/phosphorylation
//chassis/prokaryote/ecoli
//function/motility
Parameters
functiondephosphorylate CheY to move E. Coli forward
n/acheZ, chemotaxis regulator, protein phosphatase for CheY
origingenome of E. Coli BL21 Plys