Coding

Part:BBa_K5157016

Designed by: Yueheng Niu   Group: iGEM24_Jiangnan-China   (2024-09-26)


SLE linker

Usage and Biology

A short repetitive sequence selected from the region of the endogenous spacer sequence region of PETase. Molecular dynamics simulations show that it is rigid. It can be used as a rigid linker to maintain a fixed distance between the structural domains of a fusion protein and keep their independent functions [1].


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


References

[1] Chen X, Zaro J L, Shen W C. Fusion protein linkers: Property, design and functionality [J]. Advanced Drug Delivery Reviews, 2013, 65(10): 1357-1369.

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