Protein coding sequences/Biosynthesis/Odorants

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Odorants are volatile compounds that have an aroma detectable by the olfactory system. Odorant enzymes convert a substrate to an odorant product. Recently, the DNA sequences for several odorant enzymes have been obtained.


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NameProteinDescriptionDirectionUniprotKEGGE.C.SubstrateProductLengthStatus
BBa_J45008BAT2branched-chain amino acid transaminase (BAT2); converts leucine to alpha-ketoisocaproateP47176 sce:YJR148W2.6.1.42  1134In stock
BBa_J45014ATF1-1148 mutantalcohol acetyltransferase I; converts isoamyl alcohol to isoamyl acetate (banana odor)P40353sce:YOR377W2.3.1.84  1581In stock
BBa_I742107 COMT     1101In stock
BBa_J45001SAMT SAM:salicylic acid carboxyl methyltransferase; converts salicylic acid to methyl salicylate (winterQ8H6N2nonenone  1155It's complicated
BBa_J45002BAMTSAM:benzoic acid carboxyl methyltransferase; converts benzoic acid to methyl benzoate (floral odor)Q9FYZ9none2.1.1.-  1098It's complicated
BBa_J45004BSMT1SAM:benzoic acid/salicylic acid carboxyl methyltransferase I; converts salicylic acid to methyl saliQ84UB5nonenone  1074It's complicated
BBa_J45017PchA & PchBisochorismate pyruvate-lyase and isochorismate synthase (pchBA); converts chorismate to salicylate     1736It's complicated


MITiGEM2006.jpg The 2006 MIT iGEM team designed and constructed a set of protein coding regions for reprogramming bacteria to smell as wintergreen or banana.