Composite
Part:BBa_K784039:Design
Designed by: Rachel Lev Group: iGEM12_Technion (2012-09-25)
T7*(K1F) RNA polymerase + terminator
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
We planed to add T7*(K1F) RNAP primers ,that included tails with restriction site, by PCR : XbaI at the 5' end. There wasn’t any necessity to add the suffix restriction sites at the 3' because it was already at the end of the RNAP.
Source
The terminator is from the parts registry (Part:BBa_B0015). RNAP are from: Temme K., et al. 2012. Modular control of multiple pathways using engineered orthogonal T7 polymerases. Nucleic Acids Research (advance access): 1-9.