Coding

Part:BBa_K5468001

Designed by: Jiayun Sheng   Group: iGEM24_RDFZ-CHINA   (2024-09-04)


ftsE

The FtsE protein is an ATP-binding component of the ABC transporter system (ATP-binding cassette transporter) and is involved in the regulation of various cellular processes, especially those related to protein translocation and secretion. In Bacillus subtilis, FtsE plays a critical role in membrane transport, particularly in systems like the Sec-SRP (signal recognition particle) pathway, which translocates proteins from the cytoplasm to the cell membrane or extracellular environment.

FtsE functions in tandem with FtsX, forming a complex that helps regulate cell division and protein transport across membranes. In the context of surfactin production, FtsE contributes to enhancing the secretion of surfactin, a lipopeptide with biosurfactant properties. Overexpression of FtsE has been shown to increase surfactin production by improving the efficiency of its secretion from the cells. This makes FtsE a target for genetic engineering aimed at boosting industrial-scale production of surfactin for environmental applications like bioremediation.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
Parameters
None